Applications Homepage

Publication Summary: Differential Excitatory Control of 2 Parallel Basket Cell Networks in Amygdala Microcircuits

A summary of recent publication in PLOS Biology by Tibor Andrási et al, at Lendület Laboratory of Network Neurophysiology, Institute of Experimental Medicine, Hungarian Academy of Sciences.

Publication Summary: The Spatiotemporal Limits of Developmental Erk Signaling

A summary of recent publication in Developmental Cell by Heath E. Johnson, Yogesh Goayl, Nicale L. Pannucci, Trudi Schüpbach, Stanislav Y. Shvartsman, & Jared E. Toettcher, at Department of Molecular Biology, Princeton University.

Publication Summary: A Phytochrome-derived photoswitch for intracellular transport

A summary of recent publication in ACS Synthetic Biology by Max Adrian, Wilco Nijenhuis, Rein I. Hoogstraaten, Jelmer Willems, & Lukas C. Kapitein at Department of Biology, Faculty of Science, Utrecht University.

Application Note: Induction of in vitro CA1 theta-nested gamma oscillations using layer-specific optogenetic stimulation

by Department of Neuroscience, University of Cambridge,UK.

White Paper: Patterned Illumination Systems for Optogenetics

A comprehensive review of different patterned illumination technologies, including galvo-based laser scanning, holographic illumination and DMD-based patterned illumination etc.

White Paper: All-Optical Imaging & Stimulation Tools for In Vivo Neuroscience

An overview of all-optical tools for imaging and stimulation for in vivo neuroscience.

Publication in Nature Neuroscience: Sensory inputs control the integration of neurogliaform interneurons into cortical circuits

by Department of Neuroscience & Physiology, New York University, New York, New York, USA.

Customer Testimonials: Optogenetic Experiments using Polygon400 Patterned Illuminators.

Researchers from all over the world sharing their success stories on Polygon400 for their optogenetic experiments.

Polymer Photo-Patterning Using Polygon400 Patterned Illuminator

There is a great interest in developing adaptive polymer surfaces as well as patterning and assembling nanoparticles. Layer-by-layer surface patterning is used to develop functional multi-layers of organic compounds and molecules. Polygon400 can readily be used for such applications.

NeuroPG: Open Source Software for Optical Pattern Generation

Developed by the Robinson Lab at Rice University, NeuroPG is open-source software for optogenetics based on Polygon400.

Application Note: OASIS modular system for live animal optogenetic stimulation. Researchers at NYU use Mightex's OASIS to study spatio-temporal codes in the olfactory bulb of awake and behaving mice.

Application Note: Photopharmacology - New Tools for Optical Control in Biology and Medicine

Researchers at the University Toronto use Mightex LEDs to develop NIR light activated molecules opening the door to new frontiers in neuroscience and cancer research.

Polygon400 and OASIS customer base by regions

See the ever-expanding list of institutioins working with Mightex's Polygon400 and OASIS Optical Activation, Stimulation & Imaging System.

Customer Focus:
Blake Richards, PhD

An interview with Dr Richards of the University of Toronto regarding his research and how he uses the Polygon400 for his optogenetic experiments.

How to Choose an LED Controller?

Depending on your specific applications, there are usually four (4) ways to control an LED: (1) manual; (2) through software; (3) via TTL pulses; and (4) via an analog signal.

Click on the link above for a detailed LED controller selection guide.